Antipsychotics

Antipsychotics These drugs primarily work by blocking the dopamine D2 receptors in the mesolimbic and mesocortical areas of the brain. The greater the dopamine receptor binding affinity, the better the clinical potency and efficacy of the drug. They are classically...

Anti-Depressants

Anti-Depressants SSRIs Fluoxetine, sertraline, citalopram, escitalopram, paroxetine These are inhibitors of the serotonin transporter (SERT) which prevent reuptake of serotonin (5-HT) from the synaptic cleft, potentiating its action. They are first-line in the...

Immunosuppressants

Immunosuppressants These drugs are used to dampen down the immune system which is essential in the management of several inflammatory and autoimmune conditions. The first line drugs are steroids, but these cannot be used long term due to side effects, and so specific...

Pain Medicines

Pain Medicine These drugs classically work by preventing the synthesis of Prostaglandin E2 or by stimulating opioid receptors, activating brains endogenous analgesic pathways.   Opioids   Morphine This is the most famous opioid which provides analgesia in a...

Pro and Anti-Coagulants

Anticoagulants These drugs work by inhibiting specific aspects of the clotting cascade. Heparin Heparin is a natural anticoagulant produced by basophils and mast cells. Heparins work by binding to and activating antithrombin-III (AT-III). AT-III inactivates several...

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