Anti-Emetics

Anti-Emetics These drugs principally act by in inhibiting the chemoreceptor trigger zone, thereby blocking the activation of the vomiting centre in the medulla. Three of the most common first line anti-emetics are Metoclopramide + Cyclizine + Haloperidol.  D2 receptor...

PPI’s and Ant-Acids

PPIs and Ant-acids   These drugs act to reduce gastric acid production or build a protective barrier against the acid.   Inhibiting Gastric Acid secretion   Proton-Pump Inhibitors (PPI) – Omeprezole, lansoprazole, pantoprazole These drugs inhibit the...

Drugs for Smokers

Drugs used for Coughing   Coughing is a reflex response. Receptors (stretch receptors) are stimulated by irritants in the bronchial mucosa.  They signal along vagal afferents which activate the cough centre within the medulla.  Opioids – Codeine,...

Anti-inflammatory drugs

Anti-inflammatory Drugs   Anti-histaminergic drugs There are many drugs which inhibit specific parts of the histamine pathway. H1 receptor antagonists These act by blocking the H1 receptor which is Gq coupled. Therefore, this relieves bronchoconstriction and...

Drugs for Asthma/COPD

Drugs for Asthma/COPD   The primary aim of these drugs is to reverse the bronchoconstriction which is obstructing the airway to improve air flow in and out of the lungs.   B2-Adrenoceptor agonists These drugs stimulate Beta-2-adrenoceptors which result in...

Hormone Replacement Therapy (HRT)

Hormone replacement Therapy (HRT) HRT has been a revelation in the management of menopause in middle-aged women. The basic principle is to replace the oestrogen that falls during menopause to alleviate symptoms. It controls menopausal symptoms and protects against...

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