Statins and Cholesterol Modulators

Statins and Cholesterol Modulators Many drugs aim to reduce plasma cholesterol levels, as this is the main component which causes atherosclerosis, being found in LDLs.  Statins – Simvastatin, Atorvastatin These drugs inhibit cholesterol synthesis by inhibiting...

Blood Pressure Drugs

Blood Pressure Drugs Nitrovasodilators – Glyceryl trinitrate, isosorbide dinitrate These drugs are converted to nitric oxide in vascular smooth muscle cells. They activate cGMP-dependent kinases which lead to phosphorylation of MLCK, smooth muscle relaxation and...

Anti-Arrythmics

Anti-Arrythmics   Anti-arrhythmic drugs are categorised by their effects on the cardiac action potential, rather than the type of drug itself.   Class I Class I drugs bind to voltage gated Na+ channels. They have increased affinity either for the activated...

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